Interaction Study between Digoxin and a Preparation of Hawthorn [Crataegus oxyacantha]
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چکیده
منابع مشابه
Interaction study between digoxin and a preparation of hawthorn (Crataegus oxyacantha).
Hawthorn, an herbal supplement, is currently being evaluated for the treatment of heart failure. The flavonoid components of hawthorn may be responsible for hawthorn's beneficial effects in the treatment of heart failure. However, these components may also affect P-glycoprotein function and cause interactions with drugs that are P-glycoprotein substrates, such as digoxin, which is also used to ...
متن کاملProtective effects of Hawthorn (Crataegus oxyacantha) extract against digoxin-induced arrhythmias in rats
OBJECTIVE Digitalis preparations are commonly used by children and adults with heart diseases worldwide, although excessive doses may cause cardiac effects. The aim of the study is to evaluate the antiarrhythmic effect of Crataegus oxyacantha extract on digoxin-induced arrhythmias in anesthetized Wistar rats. METHODS Control and experimental groups were evaluated for arrhythmias induced by di...
متن کاملCrataegus oxyacantha Linn . commonly known as Hawthorn - A Scientific Review
Nature has been a source of medicinal agents for thousands of years and an impressive number of modern drugs has been isolated from natural sources, many based on their use in traditional medicine.Plant extracts are attractive sources of new drugs and have been shown to produce promising results in the treatment of various diseases.Crataegus oxyacantha Linn., commonly known as Hawthorn, is one ...
متن کاملCrataegus oxyacantha and Heart Failure
authors and five references. They should not have tables or figures and should relate solely to an article published in Circulation within the preceding 12 weeks. Only some letters will be published. Authors of those selected for publication will receive prepublication proofs, and authors of the article cited in the letter will be invited to reply. Replies must be signed by all authors listed i...
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ژورنال
عنوان ژورنال: Journal of Clinical Pharmacology
سال: 2003
ISSN: 0000-0000,0091-2700
DOI: 10.1177/0091270003043006009